UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Lec 09. Introduction to Chemical Biology -- RNA -- Part 2
View the complete course: http://ocw.uci.edu/courses/chem_128_i...
Instructor: Gregory Weiss, Ph.D.
License: Creative Commons BY-NC-SA
Terms of Use: http://ocw.uci.edu/info.
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Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Introduction to Chemical Biology (Chem 128) is part of OpenChem: http://ocw.uci.edu/collections/open_c...
This video is part of a 18-lecture undergraduate-level course titled "Introduction to Chemical Biology" taught at UC Irvine by Professor Gregory Weiss.
Recorded on February 7, 2013.
Index of Topics:
0:21:06 RNA and Transcription Factors
0:26:04 Comparing Bacterial and Eukaryotic mRNA Processing
0:29:08 CTP Cap Methylation
0:30:30 Using PolyA Tails to Isolate mRNA
0:34:29 Eukaryotic Splicing of mRNAs
0:37:38 RNA Degredation Plays a Major Role
0:40:40 Therapeutic Anti-Sense
0:42:32 Modifying the Oligo Backbone
0:44:20 RNA Interference Used Extensively in the Lab
0:47:57 Where Peptide Synthesis Starts
0:58:26 The Genetic Code: The Language of the Codons
1:00:33 Decoding the DNA to Protein Sequence
1:01:43 How to Load the Amino Acyl tRNA
1:06:38 Post-Translational Modification of the N-Terminus
1:07:25 Inhibiting Methionine Aminopeptidase
1:09:59 Binding to mRNA Provides Further Regulation of Translation
1:10:59 Incorporating Unnatrual Amino Acids
1:12:38 Expanding the Protein Palette
1:13:48 mRNA Aptamer Libraries
1:18:18 Puromycin Allows Covalent Linkage to the Growing Peptide During Translation
Required attribution: Weiss, Gregory Introduction to Chemical Biology 128 (UCI OpenCourseWare: University of California, Irvine), http://ocw.uci.edu/courses/chem_128_i.... [Access date]. License: Creative Commons Attribution-ShareAlike 3.0 United States License ( http://creativecommons.org/licenses/b...).
Introduction to Chemical Biology 128. Lecture 09: RNA part 2 ribosome shunting | |
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